https://ogma.newcastle.edu.au/vital/access/ /manager/Index ${session.getAttribute("locale")} 5 A randomised controlled trial of intramuscular vs. intravenous antivenom for latrodectism: the RAVE study https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:4914 20% was only 10%. In 55 patients with systemic effects, these improved in 58% after IV antivenom vs. 65% after IM antivenom (-8%; 95% CrI: -32% to +17%). Twenty-four hours after antivenom pain had improved in 84% in the IV group vs. 71% in the IM group (+13%; 95% CrI: -2% to +27%). A meta-analysis including data from a previous trial found no difference in the primary outcome between IV and IM administration. Discussion: The difference between IV and IM routes of administration of widow spider antivenom is, at best, small and does not justify routinely choosing one route over the other. Furthermore, antivenom may provide no benefit over placebo.]]> Sat 24 Mar 2018 10:14:08 AEDT ]]> Consensus guidelines for the investigation and management of encephalitis in adults and children in Australia and New Zealand https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:28270 Sat 24 Mar 2018 07:28:31 AEDT ]]>